Two disorders, PKU and Tay-Sachs, can cause mental retardation.

Question

Quizplus · Accepted Answer

Both PKU and Tay-Sachs are genetic disorders that can cause mental retardation. PKU is caused by the inability to metabolize the amino acid phenylalanine, leading to a buildup of toxic substances in the brain. Tay-Sachs is caused by a deficiency of an enzyme that breaks down a fatty substance called ganglioside, leading to a buildup of this substance in the brain and nervous system. Both disorders can result in significant intellectual and developmental disabilities if left untreated.

Two Disorders, PKU and Tay-Sachs, Can Cause Mental Retardation