Carbidopa inhibits the synthesis of dopamine in the systemic,but not central,circulation.

Question

Quizplus · Accepted Answer

Carbidopa works by inhibiting the enzyme DOPA decarboxylase, which converts levodopa to dopamine in the peripheral tissues. This allows more levodopa to cross the blood-brain barrier and increase dopamine synthesis in the central nervous system, which is where it is needed for the treatment of Parkinson's disease. Therefore, carbidopa does not inhibit dopamine synthesis in the central circulation, but it does in the systemic circulation.

Carbidopa Inhibits the Synthesis of Dopamine in the Systemic,but Not