Potential antidepressants include:

Question

Quizplus · Accepted Answer

Substance P antagonists and 5-HT1 agonists have both been shown to have antidepressant effects in preclinical and clinical studies. Substance P is a neuropeptide that is involved in stress responses and has been implicated in the development of depression. By blocking its effects, substance P antagonists may help alleviate depressive symptoms. 5-HT1 agonists, on the other hand, activate a specific subtype of serotonin receptor which has been linked to mood regulation. Together, the combination of substance P antagonism and 5-HT1 agonism may provide a synergistic antidepressant effect.

Potential Antidepressants Include