During a postmortem analysis on a sample of brain tissue, you found enlarged ventricles. This is MOST likely to be evidence of:

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Enlarged ventricles are often a sign of brain atrophy or shrinkage, which has been associated with schizophrenia involving mainly negative symptoms. This is because negative symptoms of schizophrenia are often linked to reduced brain volume in certain regions, such as the prefrontal cortex and hippocampus, which can cause the ventricles to appear enlarged on brain scans.

During a Postmortem Analysis on a Sample of Brain Tissue