A problem with accumulating a number of minor annoyances from a stress perspective is that

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Accumulating a number of minor annoyances can lead to a buildup of stress, where small amounts of stress add together to create large stress. This can lead to the development of stress-related health problems and make coping with significant stress more difficult. However, it is unlikely that only 10 minor annoyances would result in cardiac disease (A) or that a handful of minor annoyances would immediately lead to burnout (B). While accumulated stress can make it harder to cope with significant stress (C), this is not the main issue with accumulating minor annoyances.

A Problem with Accumulating a Number of Minor Annoyances from a Stress