The Mitochondrial ATP Synthase

The mitochondrial ATP synthase

A) is an entirely integral membrane protein.
B) couples the synthesis of ATP to the flow of protons across the inner membrane from inside to out.
C) is a soluble protein located in the mitochondrial matrix.
D) makes ATP at the expense of the proton gradient established by electron transport.
E) usually hydrolyzes ATP to establish a proton gradient.