Which of the following statements about the insulin receptor is false?
A) It autophosphorylates.
B) It requires binding by two insulin molecules to be activated.
C) It catalyzes the phosphorylation of insulin response substrates.
D) It is located entirely within the cytoplasm.
E) None of the above

Question

Quizplus · Accepted Answer

The insulin receptor is a transmembrane receptor that spans the plasma membrane and has an extracellular domain that binds insulin and an intracellular domain that catalyzes the phosphorylation of downstream substrates. Thus, it is not located entirely within the cytoplasm, making statement D false. Statements A, B, and C are true.

Which of the Following Statements About the Insulin Receptor Is