The second messengers derived from a phospholipid membrane lipid A) include inositol trisphospate (IP₃) and diacylglycerol (DAG). B) inhibit protein kinases. C) close Ca²⁺ channels. D) are formed from phosphatidyl choline. E) are formed from a phospholipid in the endoplasmic reticulum.

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Quizplus · Accepted Answer

The second messengers derived from a phospholipid membrane lipid include inositol trisphosphate (IPS) and diacylglycerol (DAG). IPS is formed by the hydrolysis of the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), while DAG is formed by the hydrolysis of another membrane lipid, phosphatidylcholine. IPS binds to and opens Ca2+ channels on the endoplasmic reticulum, releasing Ca2+ into the cytosol, while DAG activates protein kinase C, leading to the phosphorylation of other proteins.

The Second Messengers Derived from a Phospholipid Membrane Lipid