Which of the following represents the correct pathway for the synthesis and secretion of insulin, a protein secreted by the cells of the pancreas?
A) Rough ER, Golgi apparatus, vesicle, plasma membrane
B) Golgi apparatus, rough ER, lysosome
C) Lysosome, vesicle, plasma membrane
D) Plasma membrane, coated vesicle, lysosome
E) Rough ER, cytoplasm, plasma membrane

Question

Quizplus · Accepted Answer

Insulin is a protein hormone, synthesized and secreted by the cells of the pancreas. The correct pathway for the synthesis and secretion of insulin involves the rough endoplasmic reticulum (ER), where the protein is synthesized, followed by transport to the Golgi apparatus, where it is modified and packaged into vesicles. The vesicles containing insulin are then transported to the plasma membrane and secreted via exocytosis. Therefore, the correct pathway is rough ER, Golgi apparatus, vesicle, and plasma membrane.

Which of the Following Represents the Correct Pathway for the Synthesis