A group of transmembrane proteins involved in maintaining cell structure via their interactions with the cytoskeletion are being studied to determine their role in the spread of cancer. These proteins are known as

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Integrins are transmembrane proteins that have a crucial role in maintaining the structure of cells and their interactions with extracellular matrix (ECM). In cancer, integrins can promote tumor growth and metastasis by aiding tumor cells in invading and spreading to other tissues. Therefore, studying the role of integrins in cancer is vital for the development of effective cancer treatments. Desmosomes also play a role in cell-cell adhesion, but their main function is to hold adjacent cells together, whereas integrins bind cells to ECM. Seal tissues, connexins, and keratins are not involved in maintaining cell structure via their interactions with the cytoskeleton.

A Group of Transmembrane Proteins Involved in Maintaining Cell Structure