Which of the following must take place for a B cell to become an antibody-secreting plasma cell?

Question

Quizplus · Accepted Answer

In order for a B cell to become an antibody-secreting plasma cell, it must first be activated by binding to its specific antigen. This activation is typically done with the help of a helper T cell, which has the same specificity as the B cell's receptor. Once activated, the B cell can differentiate into plasma cells that secrete antibodies specific to the antigen. Clonal anergy refers to a state in which B cells are unresponsive to their specific antigen and is not involved in plasma cell differentiation. The production of IgE or IgG is a result of plasma cell differentiation, not a requirement for it. Activation of Class I MHC proteins is involved in presenting antigens to cytotoxic T cells, not B cell differentiation.

Which of the Following Must Take Place for a B