Untreated HIV infection will lead to a decrease in CD4-expressing T cells. Which part of the immune response is affected by this lowering of CD4-expressing T cell concentration?

Question

Quizplus · Accepted Answer

CD4-expressing T cells play a crucial role in activating and supporting the function of cytotoxic T cells and B cells. Without CD4 T cell help, the ability of cytotoxic T cells to kill target cells is impaired, and the ability of B cells to produce memory B cells is also reduced. Therefore, both options A and C are affected by the lowering of CD4-expressing T cell concentration. The ability of macrophages to recognize specific antigenic determinants is not dependent on CD4 T cell help, so option B is not affected.

Untreated HIV Infection Will Lead to a Decrease in CD4-Expressing