Hormones can exert their effects even in very low concentrations. For example, testosterone has many dramatic effects, even though its concentration in the blood of adult human males is about 30-100

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Hormones like testosterone are effective at very low concentrations, typically in the range of nanograms per milliliter, which corresponds to billionths of a gram per milliliter.

Hormones Can Exert Their Effects Even in Very Low Concentrations