The Best Way to Detect Whether Lateral Gene Transfer Has

The best way to detect whether lateral gene transfer has occurred would be by

A) looking for orphaned LTRs in the genome.
B) looking for genes whose phylogenies differ from that of most of the genes.
C) bioprospecting.
D) comparing the ratios of synonymous and nonsynonmyous substitutions.
E) comparing the transition to transversion ratios.