A biologist is examining the gene tree of a gene family of hormone receptor proteins. Which of the following should she compare when focusing on changes in function due to gene duplication?

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Paralogs are gene duplicates that arise from a gene duplication event within a species. Comparing paralogs within a gene family allows for examination of changes in function due to gene duplication. Orthologs are gene duplicates that arise from a speciation event, and although they may have diverged in function, their differences are more likely to be due to sequence variation rather than duplication-related functional changes. Analogs are genes that are similar in function but may have different evolutionary origins, and are not necessarily related by gene duplication.

A Biologist Is Examining the Gene Tree of a Gene