An example of a gain of function missense mutation is a mutation of the TP53 gene. Normally, this protein inhibits cell division, but certain mutations in the TP53 gene
A) result in a gain of an oncogenic (cancer-causing) function.
B) do not result in a change in the amino acid sequence.
C) cause the protein to stop translation and no protein is made at all.
D) cause thymine to form covalent bonds with adjacent bases.
E) result in nondisjunction.

Question

Quizplus · Accepted Answer

Certain mutations in the TP53 gene can result in a gain of function where the protein gains oncogenic (cancer-causing) properties, promoting cell division instead of inhibiting it.

An Example of a Gain of Function Missense Mutation Is