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Excess Numbers of the CGG Triplets in the FMR1 Gene

Question 65

Multiple Choice

Excess numbers of the CGG triplets in the FMR1 gene lead to clinical symptoms, including mental retardation, because the


A) triplets bind to mRNAs of other genes.
B) cytosines in the repeats are more likely to be methylated, leading to inactivation of the gene.
C) triplets cause genomic imprinting.
D) triplets make the gene so large that its mRNA cannot be transported properly.
E) triplets cause the protein to fold incorrectly.

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