A nonfunctional membrane protein is responsible for

Question

Quizplus · Accepted Answer

Cystic fibrosis is caused by a nonfunctional membrane protein called cystic fibrosis transmembrane conductance regulator (CFTR), which normally regulates the movement of salt and fluids in and out of cells. When the protein is nonfunctional, thick mucus builds up in various organs, leading to respiratory and digestive problems. Hemophilia is caused by a deficiency in blood clotting factors, sickle-cell disease is caused by a mutation in hemoglobin protein, Duchenne muscular dystrophy is caused by a mutation in the dystrophin protein, and PKU is caused by a deficiency of an enzyme needed to break down phenylalanine. None of these conditions are related to membrane proteins.

A Nonfunctional Membrane Protein Is Responsible for