The enzyme DNA ligase is required continuously during DNA replication because
A) fragments of the leading strand must be joined together.
B) fragments of the lagging strand must be joined together.
C) the parental strands must be joined back together.
D) 3'-deoxynucleoside triphosphates must be converted to 5'-deoxynucleoside triphosphates.
E) the complex of proteins that work together at the replication fork must be kept from falling apart.

Question

Quizplus · Accepted Answer

DNA ligase is required to join the Okazaki fragments that are synthesized on the lagging strand during DNA replication. These fragments are synthesized discontinuously, resulting in gaps between them that need to be sealed by DNA ligase.

The Enzyme DNA Ligase Is Required Continuously During DNA Replication