DNA damage by UV radiation causes the synthesis of
A) p53.
B) DNA.
C) Cdk.
D) cyclin.
E) p21.

Question

Quizplus · Accepted Answer

UV radiation damages DNA by causing the formation of pyrimidine dimers. This damage results in the activation of p53 and the upregulation of several downstream targets, including p21. p21 then binds to and inhibits Cdk/cyclin complexes, halting the cell cycle to allow for DNA repair. Therefore, the correct answer is E, p21.

DNA Damage by UV Radiation Causes the Synthesis of