Histones are positively charged because
A) the majority of the ions in the nucleus of the cell are negatively charged.
B) histones interact with acidic residues of proteins found in the nucleus.
C) the basic side chains of histone proteins interact with the negatively charged DNA.
D) histones have a majority of acidic residues in their protein sequence.
E) the pH of the nucleus needs to be increased.

Question

Quizplus · Accepted Answer

Histones are positively charged because their basic side chains interact with the negatively charged phosphate groups of DNA, forming strong electrostatic interactions that help to package DNA into a compact, organized structure.

Histones Are Positively Charged Because