The most stable conformation of cis-1-tert-butyl-2-methylcyclohexane is the one in which:

Question

Quizplus · Accepted Answer

The most stable conformation of cis-1-tert-butyl-2-methylcyclohexane is when the bulky tert-butyl group is in the equatorial position to minimize steric hindrance. The axial position would have more steric hindrance due to the interaction with axial hydrogens on the neighboring carbons. The methyl group is smaller than the tert-butyl group, so it is preferred in the axial position to eliminate 1,3-diaxial interactions. Thus, the best option is where the tert-butyl group is equatorial and the methyl group is axial in a chair conformation, which is option B.

The Most Stable Conformation of Cis-1-Tert-Butyl-2-Methylcyclohexane Is the One in Which