Select the structure of the major product in the following reaction.
A)I
B)II
C)III
D)IV

Question

Select the structure of the major product in the following reaction.  
A)I 
B)II 
C)III 
D)IV

Quizplus · Accepted Answer

The reaction is a Friedel-Crafts alkylation, where an isopropyl group is substituted onto the benzene ring. Only one substitution can occur due to steric hindrance caused by the bulky tert-butyl group on the ring. The most likely site for substitution is the para position relative to the nitro group, as this position offers the least steric hindrance from the nitro group. Therefore, the product is III.

Select the Structure of the Major Product in the Following