Which compound would be most reactive toward nucleophilic acyl addition-elimination? A)CH₃COCH₃ B)CH₃COCl C)(CH₃CO)₂O D)CH₃CONH₂ E)CH₃CO₂CH₃

Question

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B) CH3COCl (acetyl chloride) is most reactive toward nucleophilic acyl addition-elimination due to the presence of a good leaving group, Cl-, which makes it highly reactive towards nucleophiles.

Which Compound Would Be Most Reactive Toward Nucleophilic Acyl Addition-Elimination