Why is CH₃ONa not used in the Claisen condensation of ethyl acetate? A)CH₃O^- is a weaker base than the CH₃CH₂O^- which is used. B)CH₃O^-Na⁺ is more difficult to prepare than CH₃CH₂O^-Na⁺. C)CH₃O^- would abstract a proton from the ethyl group of the ester. D)Use of CH₃O^-Na⁺ would result in transesterification. E)CH₃O^-Na⁺ can be used as well as CH₃CH₂O^-Na⁺.

Question

Quizplus · Accepted Answer

Using CH₃O⁻Na⁺ in the Claisen condensation of ethyl acetate would result in transesterification, as the methoxide ion can exchange with the ethoxy group of the ester, leading to the formation of methyl acetate instead of the desired Claisen condensation product.

Why Is CH3ONa Not Used in the Claisen Condensation of Ethyl

Why Is CH₃ONa Not Used in the Claisen Condensation of Ethyl