If the methyl glycoside of an aldohexose is treated with HIO₄,one molar equivalent of HCHO is formed but no HCOOH.What size ring is present in the glycoside?

Question

Quizplus · Accepted Answer

The formation of one molar equivalent of HCHO (formaldehyde) but no HCOOH (formic acid) upon treatment with HIO4 indicates that the glycoside must have a five-membered ring structure. This is because the periodic acid cleavage of carbohydrates targets the vicinal diols, and in a five-membered furanose ring, the cleavage would yield formaldehyde without forming formic acid.

If the Methyl Glycoside of an Aldohexose Is Treated with HIO4,one

If the Methyl Glycoside of an Aldohexose Is Treated with HIO₄,one