It is unethical to use randomized studies to expose humans to harmful substances. Observational studies, where we compare those exposed to those not exposed, are sometimes used in such situations. Which statement describes a possibly misleading finding from such a study?
A)We can safely compare those exposed to those not exposed, as long as we have enough study subjects.
B)We have to be concerned about lurking variables, which might lead us to erroneously conclude that the compound is causing the disease.
C)If we do not carry out a randomized study, we can be sure that lurking variables will mislead us.
D)On average, an observational study will provide us with the correct conclusion.

Question

Quizplus · Accepted Answer

Lurking variables in observational studies can create associations that are not causal, leading to incorrect conclusions about the relationship between exposure and outcomes.

It Is Unethical to Use Randomized Studies to Expose Humans