In the 1840s in the United States,an initial understanding of germ theory was developed by

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Oliver Wendell Holmes, Sr., a physician and poet, wrote an essay in 1843 titled "The Contagiousness of Puerperal Fever" in which he hypothesized that the disease was caused by "something which had acquired a morbid power, by growing upon and living at the expense of the patient." This was an early understanding of germ theory, which would not be fully developed until the late 1800s.

In the 1840s in the United States,an Initial Understanding of Germ