Eukaryotic secretory proteins are synthesized and translocated via the endoplasmic reticulum. Order the following sequence of events for this process.
A.signal sequence removeD.
B.glycosylation in the ER lumen.
C.signal sequence synthesis on ribosomes.
D.SRP binds signal sequence and subsequently binds SRP-receptor.
E.ribosome dissociates.

Question

Quizplus · Accepted Answer

The correct sequence for the synthesis and translocation of eukaryotic secretory proteins starts with the synthesis of the signal sequence on ribosomes (C), followed by the binding of the signal recognition particle (SRP) to the signal sequence and its subsequent binding to the SRP receptor (D). After these steps, the signal sequence is removed (A), glycosylation occurs in the ER lumen (B), and finally, the ribosome dissociates (E).

Eukaryotic Secretory Proteins Are Synthesized and Translocated Via the Endoplasmic