Mitochondrial presequences are ____ charged amphipathic sequences retained in the ____ stage through association with ____ molecular chaperones.
A) positively; folded; Hsp40
B) positively; unfolded; Hsp70
C) negatively; folded; Hsp70
D) neutral; unfolded; Hsp40
E) negatively; prefolded; Hsp90

Question

Quizplus · Accepted Answer

Mitochondrial presequences are positively charged (due to the presence of basic amino acids such as arginine and lysine) and amphipathic (i.e. contain both hydrophilic and hydrophobic regions). These presequences are retained in the unfolded state through association with Hsp70 molecular chaperones during their translocation across the mitochondrial membranes.

Mitochondrial Presequences Are ____ Charged Amphipathic Sequences Retained in the ____

Mitochondrial Presequences Are Charged Amphipathic Sequences Retained in the