In a Class I Aminoacyl-TRNA Synthetase, Which of the Following

In a class I aminoacyl-tRNA synthetase, which of the following reacts with the acyl phosphate formed during the reaction of ATP with the amino acid?

A) 5′-hydroxyl of the nucleotide on the 5′ end of the tRNA molecule
B) 3′-hydroxyl of the nucleotide on the 5′ end of the tRNA molecule
C) 2′-hydroxyl of the nucleotide on the 5′ end of the tRNA molecule
D) 3′-hydroxyl of the nucleotide on the 3′ end of the tRNA molecule
E) 2′-hydroxyl of the nucleotide on the 3′ end of the tRNA molecule