The eukaryotic transcription factor that exhibits a sequence specificity for the TATA box is:
A) TFIIB.
B) TFIIC.
C) TFIID/TBP.
D) RNA polymerase II.
E) TFIIH.

Question

Quizplus · Accepted Answer

TFIID/TBP (Transcription Factor IID/TATA-Binding Protein) recognizes and binds specifically to the TATA box, which is important for the accurate positioning of RNA polymerase II during transcription initiation. The other transcription factors listed (TFIIB, TFIIC, TFIIH) are also involved in transcription initiation, but do not have the same sequence specificity for the TATA box that TFIID/TBP exhibits. RNA polymerase II is not a transcription factor, but rather the enzyme responsible for synthesizing the RNA transcript from the DNA template during transcription.

The Eukaryotic Transcription Factor That Exhibits a Sequence Specificity for the TATA