All Are Components of the Basic Rule of Macromolecular Recognition

All are components of the basic rule of macromolecular recognition EXCEPT:

A) protein recognizes nucleotide sequences by atomic contacts with bases and sugar-phosphate backbone usually in the major groove.
B) protein contacts involve H-bonds and salt bridges with electronegative oxygens of the phosphodiester linkages.
C) proteins present a three-dimensional shape or contour structurally and chemically complementary to the surface of the DNA sequence.
D) numerous atomic interactions underlie recognition and binding.
E) all are components.