Leptin is an important hormone that indicates a generally satisfactory amount of metabolites available in the body. Which of the following is true regarding leptin?
A) Leptin is produced in adipose tissue in response to the presence of large amounts of triacylglycerols
B) One of the results of leptin production is the increase in thermogenesis in adipose tissue brought about through an increase in the expression of thermogenin
C) The primary site of leptin's action is upon the hypothalamus where it ultimately results in the release of norepinephrine
D) All of the above are correct
E) A and C are correct

Question

Quizplus · Accepted Answer

Leptin is indeed produced in adipose tissue in response to the presence of large amounts of triacylglycerols (A), and it does increase thermogenesis in adipose tissue through an increase in the expression of thermogenin (B). Its primary site of action is the hypothalamus, where it influences energy expenditure and food intake, although the specific mention of norepinephrine release is a simplification of its complex effects on the hypothalamus (C). Therefore, all of the statements provided are correct in the context of leptin's functions and effects.

Leptin Is an Important Hormone That Indicates a Generally Satisfactory