What is the function of phosphoribosyltransferases?
A) they are involved in the reversible reactions of purine salvage.
B) they mediate the degradation of AMP.
C) they are central to the re-synthesis of nucleotides from bases in salvage reactions.
D) they mediate the degradation of IMP.
E) they are competitive inhibitors employed in the salvage of purine nucleotides.

Question

Quizplus · Accepted Answer

Phosphoribosyltransferases are enzymes that catalyze the transfer of a phosphoribosyl group from phosphoribosyl pyrophosphate (PRPP) to a nitrogenous base, creating a nucleotide. This process is central to the re-synthesis of nucleotides from bases in salvage reactions. Purine salvage is an example of such salvage reactions, and phosphoribosyltransferases are involved in the reversible reactions of purine salvage. Additionally, phosphoribosyltransferases are not involved in the degradation of nucleotides, such as AMP or IMP. They are also not competitive inhibitors.

What Is the Function of Phosphoribosyltransferases