The correct sequence for synthesis of mevalonate from acetyl-CoA is:
A.HMG-CoA synthase
B.formation of 3-hydroxy-3-methylglutaryl-CoA
C.β-ketothiolase catalyzed condensation
D.HMG-CoA reductase activity
E.Formation of acetoacetyl-CoA

Question

Quizplus · Accepted Answer

The correct sequence for the synthesis of mevalonate from acetyl-CoA involves the formation of acetoacetyl-CoA (E), followed by the β-ketothiolase catalyzed condensation (C), leading to the formation of 3-hydroxy-3-methylglutaryl-CoA (B), which is then catalyzed by HMG-CoA synthase (A), and finally, the HMG-CoA reductase activity (D) converts it into mevalonate.

The Correct Sequence for Synthesis of Mevalonate from Acetyl-CoA Is