Pyruvate carboxylase consumes a(n) ____ to drive a carboxylation so that ____ could use the energy from decarboxylation to facilitate formation of PEP.

Question

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Pyruvate carboxylase consumes ATP to drive the carboxylation of pyruvate, creating oxaloacetate. This oxaloacetate can then be converted to phosphoenolpyruvate (PEP) by the enzyme PEP carboxykinase, which requires energy from decarboxylation. Therefore, option D is the correct choice. Option A is incorrect because NADH is not used to drive pyruvate carboxylation. Lactate dehydrogenase (option B) is not involved in pyruvate carboxylation. Pyruvate kinase (option C) does not use pyruvate as a substrate and is not involved in carboxylation reactions. Nucleotide diphosphate kinase (option E) is not involved in pyruvate carboxylation.

Pyruvate Carboxylase Consumes A(n) ____ to Drive a Carboxylation So