If an ATP synthase contains 12 c subunits, 3 α subunits and 3 β subunits, how many protons must pass through this complex for every ATP molecule synthesized and transported to the cytosol, assuming that each ATP synthesized requires one proton for transport to the cytosol.

Question

Quizplus · Accepted Answer

Each ATP molecule synthesized requires the rotation of the c ring by one complete turn, which involves the passage of 12 protons (one for each c subunit). Since 3 ATP molecules are produced per full rotation, 12 protons are needed for synthesis, and an additional proton is required for transport of each ATP to the cytosol, totaling 5 protons per ATP.

If an ATP Synthase Contains 12 C Subunits, 3 α