The correct sequence of steps between succinyl-CoA and ATP in mammals to "preserve" the energy of the thioester bond are:
A.succinyl-phosphatE.
B.phosphohistidinE.
C.GTP.
D.Acetyl-CoA.

Question

Quizplus · Accepted Answer

The correct sequence is A, B, C to preserve the energy of the thioester bond in mammals. Succinyl-CoA is converted to succinyl-phosphate through phosphorylation, preserving the energy of the thioester bond in the phosphate ester bond. Succinyl-phosphate then transfers its phosphate group to a histidine residue on the enzyme succinate thiokinase, forming phosphohistidine. Finally, the energy of the thioester bond is used to convert GDP to GTP, which directly transfers a phosphate group to ADP to form ATP. Therefore, the correct sequence is A, B, C for preserving the energy of the thioester bond in mammals.

The Correct Sequence of Steps Between Succinyl-CoA and ATP in Mammals