All are important reasons to phosphorylate glucose in the first step of glycolysis EXCEPT:

Question

Quizplus · Accepted Answer

The large positive free energy change is not a reason for phosphorylating glucose in glycolysis. The phosphorylation of glucose by hexokinase (or glucokinase in liver cells) to form glucose-6-phosphate is actually coupled with the hydrolysis of ATP to ADP, which is an energetically favorable reaction. This step is important for trapping glucose within the cell, preventing its transport out, lowering its intracellular concentration to favor further uptake, and providing a means of regulatory control.

All Are Important Reasons to Phosphorylate Glucose in the First