Seven of the ten reactions of glycolysis are reversible (ΔG near zero) and can be used in reverse of glycolysis for gluconeogenesis. The three irreversible reactions are catalyzed by:

Question

Quizplus · Accepted Answer

The question asks for the enzymes catalyzing the three irreversible reactions in glycolysis. These are the steps that have a large negative ΔG, meaning they are essentially irreversible. The three irreversible steps are the conversion of glucose to glucose-6-phosphate by hexokinase, the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase-1, and the conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase. Therefore, the best choice is E, which contains all three of these enzymes.

Seven of the Ten Reactions of Glycolysis Are Reversible (ΔG