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In the Hydrolysis of P-Nitrophenylacetate by Chymotrypsin All of the Following

Question 1

Multiple Choice

In the hydrolysis of p-nitrophenylacetate by chymotrypsin all of the following are correct EXCEPT:


A) the first product is acetic acid.
B) an acetyl-enzyme intermediate forms during the mechanism.
C) attack of a water molecule on the acyl-enzyme intermediate yields the second product.
D) the active site contains a serine residue, an unprotonated histidine, and an unprotonated aspartate residue at pH 7.0 prior to binding the substrate.
E) none of the above.

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