Which statement is correct about the Michaelis-Menten constant, K_m, for the kinetic mechanism below? A) It is numerically equal to the substrate concentration required to achieve one half the maximum velocity. B) Its defined as K_m = k₁/(k−₁ + k₂). C) It is approximately equal to the dissociation constant for the enzyme-substrate complex to E + P. D) The value of K_m is constant for an enzyme regardless of the specific substrate molecule used to determine it. E) Its numeric value has the units of moles−¹.

Question

Quizplus · Accepted Answer

The Michaelis-Menten constant, K_m, is defined as the substrate concentration at which the reaction velocity is half of the maximum velocity. Therefore, choice A is the correct statement. Choice B is the definition of the Michaelis-Menten equation. Choice C is a statement about the dissociation constant, KD, for the enzyme-substrate complex, which is related to K_m but not equal to it. Choice D is false because the value of K_m depends on the specific substrate molecule. Choice E is false because K_m does not have units of moles−¹.

Which Statement Is Correct About the Michaelis-Menten Constant, Km, for the Kinetic

Which Statement Is Correct About the Michaelis-Menten Constant, K_m, for the Kinetic