Which of the following explains why it is often easier to sequence a gene rather than sequence the corresponding protein?
A) DNA sequencing can be performed on picogram quantities of DNA
B) DNA is composed of only 4 different monomers while proteins are composed of 20 different monomers
C) restriction endonucleases can be used to cut DNA at specific sequences to generate DNA fragments that can easily be sequenced
D) all of the above
E) both B and C are correct

Question

Quizplus · Accepted Answer

DNA sequencing technologies allow for the sequencing of very small quantities of DNA, and the simpler monomeric structure of DNA (4 nucleotides) compared to proteins (20 amino acids) makes the process more straightforward. Additionally, the use of restriction endonucleases to specifically cut DNA facilitates the generation of manageable fragments for sequencing.

Which of the Following Explains Why It Is Often Easier