Edman degradation will:
A) determine the C-terminal amino acid by using a carboxypeptidase.
B) cleave the protein into a multitude of smaller peptides.
C) compare overlapping sets of peptide fragments.
D) determine the N-terminal amino acid.
E) generate two different, but overlapping sets of peptide fragments.

Question

Quizplus · Accepted Answer

Edman degradation is a technique that sequentially removes the N-terminal amino acid from a protein, allowing for identification of the amino acid sequence. Therefore, option D is the correct choice.

Edman Degradation Will