O6-methylguanine has a high probability of base pairing with thymine to result in a post replication mutation from a GC base pair to:

Question

Quizplus · Accepted Answer

O6-methylguanine primarily pairs with thymine during DNA replication, leading to a mispairing of bases. The correct base pairing for thymine is adenine, but since the O6-methylguanine has altered the guanine, it cannot recognize adenine as the correct partner. Therefore, during replication, the methylated guanine base pairs with thymine instead of its correct pair, cytosine, resulting in a GC to AT mutation.

O6-Methylguanine Has a High Probability of Base Pairing with Thymine