Which of the following does NOT apply to the reaction catalyzed by the pyruvate dehydrogenase complex?
A) The process is highly exergonic and essentially irreversible in vivo.
B) Each intermediate in the five step reaction is able to diffuse to the next active site in a sequential manner.
C) It takes place in the mitochondrion.
D) It is an oxidative decarboxylation.
E) The product is acetyl CoenzymeA.

Question

Quizplus · Accepted Answer

The reaction catalyzed by the pyruvate dehydrogenase complex is not a sequential reaction in which intermediates diffuse to the next active site in order. Instead, the intermediates are bound to specific active sites within the complex and undergo a series of coordinated reactions.

Which of the Following Does NOT Apply to the Reaction