Integral membrane proteins can be inserted into the membrane and folded into the normal 3D structure during translation.

Question

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Integral membrane proteins have hydrophobic regions that allow them to embed themselves into the lipid bilayer of the membrane. This process can occur during translation, with the protein folding into its proper 3D structure as it is being transferred to the membrane.

Integral Membrane Proteins Can Be Inserted into the Membrane and Folded