Drugs administered transdermally must be:
A) lipophilic.
B) hydrophilic.
C) lipophobic.
D) amphipathic.

Question

Quizplus · Accepted Answer

Drugs administered transdermally must be lipophilic, which means they can dissolve and pass through the skin's lipid barrier to reach the bloodstream. Hydrophilic drugs, which do not readily dissolve in lipids, are not well-suited for transdermal administration. Lipophobic drugs are not attracted to lipids and would not pass through the skin's barrier. Amphipathic drugs have both hydrophobic and hydrophilic properties, but lipophilicity is the key requirement for transdermal administration.

Drugs Administered Transdermally Must Be