Suppositories,in general,when inserted into the lower third of the rectum:
A) always have a fast onset of action.
B) avoid the hepatic first pass.
C) are useful for ulcerative colitis.
D) are for laxative use only.

Question

Quizplus · Accepted Answer

Suppositories inserted into the lower third of the rectum bypass the hepatic first pass metabolism, which can decrease the amount of drug degraded and increase bioavailability. However, the other options are not true for all suppositories. The onset of action, usefulness for specific conditions, and indication for laxative use vary depending on the type of suppository.

Suppositories,in General,when Inserted into the Lower Third of the Rectum